ʻO ka moa Collagen ʻano ii ʻole no ke Ola Hui
inoa mea | ʻO ka moa Collagen ʻano ii ʻole no ke Ola Hui |
Ke kumu o ka mea | ʻūhā moa |
Ka nana aku | Keʻokeʻo i ka pauka melemele liʻiliʻi |
Kaʻina hana hana | Kaʻina hydrolyzed wela haʻahaʻa |
Kolagen ano ii undenatured | >10% |
Huina pūmua | 60% (Kjeldahl ala) |
ʻoluʻolu | ≤10% (105° no 4 mau hola) |
ʻAno nui | >0.5g/ml e like me ka nui o ka nui |
Ka hoʻoheheʻe | Hoʻoheheʻe maikaʻi i ka wai |
Palapala noi | No ka hana ʻana i nā mea hoʻohui mālama hui |
Ola Pahu | 2 makahiki mai ka lā hana |
Hoʻopili | Hoʻopili i loko: ʻeke PE i hoʻopaʻa ʻia |
Hoʻopili waho: 25kg/Drum |
ʻO ka moa kolagen type II ka ʻano II collagen i hana ʻia mai ka moa sternum ma lalo o kahi kaʻina hana i hoʻomalu maikaʻi ʻia a hoʻomohala ʻia i mea e hoʻokaʻawale ʻole ai ka protein o ka collagen.ʻO ka huaʻōlelo "Undenatured" ʻo ia ke ʻano o ka molecular structure o ke ʻano ii collagen i noho i loko o ka Triple Helix Structure e like me ke ʻano i loko o ke kino holoholona ma hope o ka unuhi ʻia a hoʻopaʻa ʻia mai ka sternum moa.
ʻO ke ʻano collagen moa ʻole i hoʻopaʻa ʻia ʻo ia ka collagen ikaika e noho mau ana i loko o kona ʻano mole mole ʻeleʻele ʻoiai ua nalowale ka hana o ka collagen denatured ma ke kaʻina hydrolyzation.He mea koʻikoʻi ka molekele hana o ka collagen no ka hana ʻana o ka collagen i ka pane ʻana i ka pale ʻana i kekahi ʻano o ka mumū o nā maʻi hui.
ʻO ke ʻano II collagen ʻo ia ke kumu nui o ka collagen i loko o nā cartilages hui.ʻO ka Glycosaminoglycan i loko o ke ʻano ii collagen he mea nui o ka iwi a me ka cartilage articular o ka lua hui synovial.Kōkua ia i ka hoʻomaikaʻi ʻana i nā cartilages a me ka lubrication hui.
PARAMETER | OLELO HOOLAHA |
Ka nana aku | Keʻokeʻo i ka pauka keʻokeʻo |
Hui Pūʻai | 50%-70% (Kjeldahl Method) |
Kolagen ano II ole | ≥10.0% (Keʻano Elisa) |
Mucopolysaccharide | ʻAʻole emi ma lalo o 10% |
pH | 5.5-7.5 (EP 2.2.3) |
Koe ma ka Ignition | ≤10%(EP 2.4.14 ) |
Pohō ma ka maloʻo | ≤10.0% (EP2.2.32) |
Metala Kaumaha | < 20 PPM(EP2.4.8) |
Ke alakaʻi | <1.0mg/kg(EP2.4.8) |
Mercury | <0.1mg/kg(EP2.4.8) |
Cadmium | <1.0mg/kg(EP2.4.8) |
Arsenic | <0.1mg/kg(EP2.4.8) |
Helu Bacteria Huina | <1000cfu/g(EP.2.2.13) |
Huna & Mold | <100cfu/g(EP.2.2.12) |
E.Coli | ʻAʻole/g (EP.2.2.13) |
Salmonella | ʻAʻole/25g (EP.2.2.13) |
ʻO Staphylococcus aureus | ʻAʻole/g (EP.2.2.13) |
1. Kiʻekiʻe maʻiʻo o undenatured collagen type ii: ʻO kā mākou undenatured collagen type ii i hana ʻia e kahi kaʻina hana kūʻokoʻa, e mālama ana i ka hana o ka collagen a ma ka manawa like e hoʻomaʻemaʻe i ka mea e loaʻa i kahi kiʻekiʻe o ka collagen undenatured.Loaʻa i nā mea hana ʻē aʻe ma kahi o 3%, 9% undenatured collagen type ii hiki iā mākou ke hoʻolako a hiki i 25% undenatured collagen type ii.
2. Kiʻekiʻe Bulk density me ka maikaʻi flowability: ʻO kā mākou undenatured collagen type II he kiʻekiʻe kiʻekiʻe ma kahi o 0.5g / ml a me ka flowability maikaʻi, kahi e kūpono ai ke hana i nā papa a i ʻole capsules.
3. ʻO ka maikaʻi GMP: ʻO ka pauka kolagen a mākou i hoʻolako ai i hana ʻia ma ka hale GMP e like me nā koi GMP.Hoʻāʻo ʻia i loko o kā mākou hale hana ponoʻī ma mua o ka hoʻokuʻu ʻana i nā waiwai iā ʻoe.
1. Kōkua i ka ho'ēmi ʻana i ka mumū i hoʻokumu ʻia e ka pane ʻana i ke kino e kūʻē i ka endogenous type II collagen, i ʻike ʻia ʻo ka autoimmune intolerance.
Mālama ka Undenatured collagen type II i ka ʻano triple helix kūlohelohe e paʻa ana i kahi kumu antigenic, kahi e loaʻa ai i ka collagen kahi hiki ke hoʻopaʻa antigen-antibody.Hiki mai ka rheumatoid arthritis i ka wā e hana ai ke kino i kekahi mau antibodies e kū'ē i nā autoantigens.Hōʻike ka noiʻi hou loa i ka lawe ʻana i kahi haʻahaʻa haʻahaʻa o ka collagen type II e hoʻowalewale i ke kino e noʻonoʻo i ka protein type II ma ke ʻano he antigen ponoʻī, kahi e pale ai i ka hanauna o autoantibody.Ma kēia ʻano, e hoʻolohi i nā maʻi o ka maʻi rheumatoid arthritis.
2. Aia i loko o ka Undenatured collagen type ii nā glycosaminoglycans he nui.ʻO ka hui pū ʻana o nā glycosaminoglycans a me nā protein koʻikoʻi e kōkua i ka hoʻoulu ʻana o nā proteoglycans i nā cartilages.Ma kēia ala, hoʻihoʻi ka collagen type II i ke koena o ke kūkulu hou ʻana i ka ʻiʻo cartilage a me ka hoʻoponopono ʻana i nā cartilage i hōʻino ʻia.
3. ʻO ke ʻano collagen Undenatured ii ka nui o ka hydroxyproline ma mua o ka collagen type maʻamau, ʻoi aku ka maikaʻi o ka hoʻopili ʻana o ka calcium, phosphorus a me nā mea mineral ʻē aʻe e lilo i iwi.No laila, hoʻohana nui ʻia ia ma ke ʻano he mea hoʻohui no nā mea hoʻohui olakino.
Hōʻike ka haʻawina ʻepekema e hāʻawi ka AC-II i nā pono no ke olakino hui.Hōʻike ka noiʻi lapaʻau i nā holoholona e hōʻoia ʻia nā pōmaikaʻi o AC-II i nā hoʻāʻo o ka osteoarthritis traumatic, post-traumatic a me ka obesity-induced arthritis o nā ʻiole.
I ka ho'āʻo ʻana o ka osteoarthritis post-traumatic, ua hōʻino ʻia ka hui ʻana i ka nalo ʻana o ka cartilage (matrix a me chondrocytes) a me ka mumū kūloko o ka hui kuli.Ma hope o ka lawe ʻana i ka Active Collagen II haʻahaʻa haʻahaʻa, ua hōʻike maopopo ʻia kēia mau pōmaikaʻi:
1. Kāohi i ka hoʻohaʻahaʻa a me ka lubrication cartilage
Hiki i ka AC-II ke pale i ka cartilage a ho'ēmi i nā loli degenerative (normalization o chondroitin region, blue bars ma kaʻaoʻao hema o ke kiʻikuhi ma lalo), hoʻoulu i ka proteoglycan synthesis i loko o nā chondrocytes a hoʻoikaika i ka lubrication hui (piʻi ka pakeneka o nā chondrocytes hoʻoikaika, e like me ka mea i hōʻikeʻia ma ka polū. histogram ma ka ʻaoʻao ʻākau o ke kiʻikuhi ma lalo).
Diagram No.1: Undenatured Chicken Collagen type ii Kāohi i ka hōʻino ʻana o ka cartilage a hoʻoikaika i ka synthesis o nā matrices lubricating.
2. E ho'ēmi i ka mumū
Undenatured moa collagen type ii paipai i ka anti-inflammatory hopena o ka hui kuli (hoemi i ka hoike ana o ka kūloko inflammatory markers i loko o ka synovial membrane, E nana uliuli histogram ma lalo kiʻi).
Diagram No.2: ʻO ka moa collagen type ii i hoʻemi ʻole ʻia i ka ʻā o ka OA.
3. Kāohi i ka OA (Osteoarthritis)
I ka hoʻāʻo ʻana o ka osteoarthritis obese a traumatic, ʻo ka nalowale ʻana o ka cartilage ami kuli (matrix a me chondrocytes) a me ka pane inflammatory kūloko i hoʻohuli ʻia.Haʻahaʻa-haʻahaʻa
Hiki i ka hoʻohui ʻia ʻana o ka moa collagen type II ke pale i ka osteoarthritis ma lalo o nā ʻano:
Ua hōʻike ʻia nā hoʻokolohua ʻana i nā ʻiole i paʻa i nā meaʻai momona kiʻekiʻe i ka pale ʻana i ka cartilage, ka emi ʻana o nā loli degenerative (Cartilage zone normalization, blue histogram ma ka ʻaoʻao hema o ke kiʻi ma lalo), a me ka hoʻoikaika ʻana i ka lubrication hui ma ka hoʻoulu ʻana i ka synthesis proteoglycan i loko o nā chondrocytes ( Hoʻonui ka pākēneka o nā chondrocytes i hoʻāla ʻia, ka histogram polū ma ka ʻaoʻao ʻākau o ke kiʻi ma lalo).
Diagram No.3 : ʻO ka moa i hoʻokaʻawale ʻole ʻia ʻo Collagen type ii e pale i ka hōʻino ʻana o ka cartilage a hoʻoikaika i ka synthesis o kahi matrix lubricating i ka osteoarthritis i hoʻokumu ʻia e ka momona.
4. Bioavailability kiʻekiʻe
Hōʻike ka haʻawina i ka hola 1 ma hope o ka lawe ʻana i ke ʻano Undenatured ii i ka hydroxyproline i loko o ka serum ʻiole i kahi kiʻekiʻe kiʻekiʻe, e hōʻoiaʻiʻo ana i ka ʻano moa Undenatured ii he bioavailability kiʻekiʻe.
Kiʻikuhi 4: ʻO ka moa i hoʻopaʻa ʻole ʻia ʻo Collagen type ii hiki ke hoʻomohu pono ʻia e ke kino.
ʻO ka mea maʻamau, hoʻohana ʻia ka ʻano kolagen undenatured ʻano II no ka hana ʻana i ka capsule paʻakikī i loaʻa i ka moa kolagen ʻano Undenatured ii.Hiki ke hoʻohana pū ʻia me nā mea olakino ʻē aʻe e like me chondroitin sulfate, glucosamine a me hyaluronic acid.
ʻO ke ʻano hana hoʻopau kaulana loa no ka moa collagen type ii ʻaʻole i hoʻopaʻa ʻia ʻo ia ʻo Bone a me nā capsule olakino hui.ʻO kā mākou moa kolagen ʻano ii ʻano ʻole he kahe maikaʻi a hiki ke hoʻopiha ʻia i loko o nā capsules maʻalahi.
Ka hua'ōlelo kalepa: MOQ, hāpana a me ke kumu kūʻai
Hoʻopili: ʻO kā mākou paʻi ʻana he 25KG / Drum no nā kauoha kālepa nui.No ka liʻiliʻi liʻiliʻi kauoha, hiki iā mākou ke hana i ka hoʻopili ʻana e like me 1KG, 5KG, a i ʻole 10KG, 15KG i loko o nā ʻeke Aluminum foil.
Kumukānāwai Laʻana: Hiki iā mākou ke hāʻawi i ka 30 grams me ka uku ʻole.Hoʻouna pinepine mākou i nā laʻana ma o DHL, inā he moʻokāki DHL kāu, e ʻoluʻolu e kaʻana like me mākou.
Kumukūʻai: E ʻōlelo mākou i nā kumukūʻai e pili ana i nā kikoʻī like ʻole a me nā nui.
Hana Hana: Ua hoʻolaʻa mākou i ka hui kūʻai aku e hana i kāu mau nīnau.Hoʻohiki mākou e loaʻa iā ʻoe kahi pane i loko o 24 mau hola mai kou hoʻouna ʻana i kahi nīnau.