ʻO ka collagen, kahi ʻano protein i kūkulu ʻia i loko o ka matrix extracellular, ua kapa ʻia ʻo Collagen, i ulu mai ka Helene.ʻO ka Collagen kahi protein fibrous keʻokeʻo, opaque a ʻaʻole lālā i loaʻa i ka ʻili, iwi, cartilage, niho, tendons, ligaments a me nā kīʻaha koko o nā holoholona.He mea koʻikoʻi koʻikoʻi ia o ka hoʻokumu ʻana o nā ʻiʻo pili, a he hana i ke kākoʻo ʻana i nā kino a me ka pale ʻana i ke kino.ʻO Collagen ka nui o ka protein i loko o nā mammals, e helu ana no 25% a 30% o ka nui o ka protein i loko o ke kino, e like me 6% o ke kaumaha o ke kino.
I kēia mau makahiki i hala iho nei, me ka hoʻomohala ʻana o ka ʻenehana hōʻiliʻili collagen a me nā noiʻi hohonu e pili ana i kona ʻano a me nā waiwai, ua ʻike nui ʻia nā hana biological o collagen hydrolysates a me polypeptides.Ua lilo ka noiʻi a me ka hoʻohana ʻana i ka collagen i wahi hotspot noiʻi i ka lāʻau lapaʻau, ka meaʻai, nā mea hoʻonaninani a me nā ʻoihana ʻē aʻe.
Ma waho aʻe o ka tryptophan a me ka cysteine, aia ka collagen i 18 amino acids, 7 o ia mau mea pono no ka ulu ʻana o ke kanaka.ʻO ka glycine i loko o ka collagen he 30%, a ʻo ka proline a me ka hydroxyproline i hui pū ʻia ma kahi o 25%, ʻo ia ka mea kiʻekiʻe loa ma waena o nā ʻano protein āpau.He kiʻekiʻe nō hoʻi ka ʻike o ka alanine a me ka glutamic acid.Eia kekahi, aia ka hydroxyproline a me ka pyroglutamic acid, ka mea i ʻike ʻole ʻia i nā protein maʻamau, a me ka hydroxyllysine, ka mea i ʻaneʻane ʻaʻole i loko o nā protein ʻē aʻe.
ʻO ka Collagen kahi pūmua i kūkulu ʻia i loko o ka matrix extracellular kahi i hoʻohui ʻia ai kona mau molekole i loko o nā hale supramolecular.ʻO 300 ku ke kaumaha molekala.ʻO ka hiʻohiʻona maʻamau o ka collagen he triple helix structure, ʻo ia hoʻi ʻekolu alpha polypeptides i loko o ke kaula alpha lima hema, ua wili ʻia kēlā me kēia a puni e hana i kahi ʻano alpha helix lima ʻākau.
ʻO ka hanana triple helix kū hoʻokahi o ka collagen e hoʻokūpaʻa loa i kāna ʻano molekala, a he haʻahaʻa immunogenicity a me ka biocompatibility maikaʻi.Hoʻoholo ka hale i ka waiwai, a hoʻoholo ka waiwai i ka hoʻohana.ʻO ka ʻokoʻa a me ka paʻakikī o ka hoʻolālā collagen e hoʻoholo i kona kūlana koʻikoʻi ma nā kahua he nui, a he manaʻo maikaʻi nā huahana collagen.
ʻO Collagen kahi ʻohana o nā protein.Ma kahi o 30 mau genes coding o nā kaulahao collagen i loaʻa, hiki ke hana ʻia ma mua o 16 mau ʻano molekele collagen.E like me kā lākou mahele a me nā hiʻohiʻona hana i loko o vivo, ua māhele ʻia ka collagen i ka collagen interstitial, basal membrane collagen a me pericellular collagen.ʻO nā molekala collagen interstitial no ka hapa nui o ka collagen i ke kino holoʻokoʻa, me ke ʻano Ⅰ, Ⅱ a me Ⅲ collagen mole, ka mea i māhele nui ʻia i ka ʻili, tendon a me nā ʻiʻo ʻē aʻe, ma waena o nā ʻano Ⅱ collagen i hana ʻia e chondrocytes.ʻO ka collagen membrane basement ka mea maʻamau i kapa ʻia ʻo ke ʻano Ⅳ collagen, ka mea i māhele nui ʻia i ka membrane basement.ʻO kolagen pericellular, ʻano maʻamau ʻo Ⅴ collagen, aia i ka nui i loko o ka ʻiʻo pili.
ʻO kā mākou Packing he 25KG collagen type i hoʻokomo ʻia i loko o kahi ʻeke PE, a laila hoʻokomo ʻia ka ʻeke PE i loko o ka pahu fiber me kahi laka.Hoʻopili ʻia nā pahu 27 ma luna o hoʻokahi pallet, a hiki i kahi pahu 20 kapuaʻi ke hoʻouka ma kahi o 800 pahu he 8000KG inā palleted a me 10000KGS inā ʻaʻole palleted.
Loaʻa nā laʻana manuahi ma kahi o 100 grams no kāu hoʻāʻo ʻana ma ke noi.E ʻoluʻolu e kelepona mai iā mākou e noi i kahi laʻana a i ʻole ka ʻōlelo.
Loaʻa iā mākou nā hui kūʻai ʻoihana e hāʻawi i ka pane wikiwiki a pololei i kāu mau nīnau.Hoʻohiki mākou e loaʻa iā ʻoe kahi pane i kāu nīnau i loko o 24 mau hola.
Ka manawa hoʻouna: Dec-05-2022